Publications

  1. Ko KP, Kim SM, Jang J, Seo Y, Zou G, Zhang J, Jun S, Morrow B, Park RJ, Lo YH, Ajani JA, Curran MA, Kim HK, Park JI, RHOA Y42C-driven cell lineage plasticity and immune remodeling in diffuse gastric cancer. (Accepted)

  2. Jang J*, Ko KP*, Zhang J, Jun S, Park JI. Deciphering Precursor Cell Dynamics in Esophageal Preneoplasia via Genetic Barcoding and Single-Cell Transcriptomics. Proceedings of the National Academy of Sciences, 2025 Dec 9;122(49):e2509534122. doi: 10.1073/pnas.2509534122. Epub 2025 Dec. PubMed PMID: 41337486; PubMed Central PMCID: PMC11888434.

  3. Seo Y*, Zhang S*, Jang J*, Ko KP*, Kim KB*, Huang Y*, Kim DW, Kim B, Zou G, Zhang J, Jun S, Chu W, Kirk NA, Hwang YE, Ban YH, Dhar SS, Chan JM, Lee MG, Rudin CM, Park KS, Park JI. Actin Dysregulation Induces Neuroendocrine Plasticity and Immune Evasion: A Vulnerability of Small Cell Lung Cancer. Nature Communications. 2025 Dec 6. doi: 10.1038/s41467-025-67078-9. PubMed PMID: 41353272; PubMed Central PMCID: PMC9949038.

  4. Ko KP, Park JI, Genetic Engineering of Esophageal Organoids: CRISPR-Based Knock-In for Cell Lineage Tracing. Methods in Molecular Biologly, 2025 Oct 11. doi: 10.1007/7651_2025_669. PubMed PMID: 41071231.

  5. Ko KP, Zhang J, Jun S, Park JI. Single-cell lineage trajectory defines CDK inhibitor-sensitive cells-of-origin in esophageal squamous cell cancer. Gastro Hep Advances  2025 Dec 29; doi: https://doi.org/10.1016/j.gastha.2025.100874. eCollection 2026. PubMed PMID: 41641362; PubMed Central PMCID:  PMC12865637.

  6. Ko KP, Zhang S, Huang Y, Kim B, Zou G, Jun S, Zhang J, Zhao Y, Martin C, Dunbar KJ, Efe G, Rustgi AK, Nakagawa H, Zhang H, Liu Z, Park JI. Tumor Niche Network-Defined Subtypes Predict Immunotherapy Response of Esophageal Squamous Cell Cancer. iScience. 2024 May 17;27(5):109795. doi: 10.1016/j.isci.2024.109795. eCollection 2024 May 17. PubMed PMID: 38741711; PubMed Central PMCID: PMC11089351.

  7. Ko KP, Huang Y, Zhang S, Zou G, Kim B, Zhang J, Jun S, Martin C, Dunbar KJ, Efe G, Rustgi AK, Nakagawa H, Park JI. Key genetic determinants driving esophageal squamous cell carcinoma initiation and immune evasion. Gastroenterology. 2023 Sep;165(3):613-628.e20. doi: 10.1053/j.gastro.2023.05.030. Epub 2023 May 29. PubMed PMID: 37257519; PubMed Central PMCID: PMC10527250.

  8. Ko KP, Zhang J, Park JI. Establishing transgenic murine esophageal organoids. STAR Protoc. 2022 Apr 21;3(2):101317. Epub 2022/05/03. doi: 10.1016/j.xpro.2022.101317. PubMed PMID: 35496812; PMCID: PMC9048136.

  9. Zheng B*, Ko KP*, Fang X, Wang X, Zhang J, Jun S, Kim BJ, Luo W, Kim MJ, Jung YS, Cervantes CL, Park JI. A new murine esophageal organoid culture method and organoid-based model of esophageal squamous cell neoplasia. iScience. 2021 Nov 15;24(12):103440. Epub 2021/12/09. doi: 10.1016/j.isci.2021.103440. PubMed PMID: 34877497; PMCID: PMC8633967.

  10. Ko KP, Jeong SI, Lim JS, Lee KW, Lee MG, Chi SG. NORE1A directs apoptotic switch of TNF signaling through reciprocal modulation of ITCH-mediated destruction of TNFRI and BAX. Oncogene. 2020 Aug;39(34):5675-89. Epub 2020/07/22. doi: 10.1038/s41388-020-01392-y. PubMed PMID: 32690868.

  11. Hou JT*, Ko KP*, Shi H, Ren WX, Verwilst P, Koo S, Lee JY, Chi SG, Kim JS. PLK1-Targeted Fluorescent Tumor Imaging with High Signal-to-Background Ratio. ACS Sens. 2017 Oct 27;2(10):1512-6. Epub 2017/09/19. doi: 10.1021/acssensors.7b00544. PubMed PMID: 28920432.

    * equal contribution